Graphene quantum dots for tumor optical diagnosis and treatment
Graphene quantum dots (GQDs)are two-dimensional carbon nano-material with excellent physicochemical properties,including biocompatibility,high photoluminescence,water-solubility,hypotoxicity and so on.Owing to big π-conjugated structure and oxygen-containing functional groups,GQDs have the ability to absorb various chemical drugs via π-π stacking and electrostatic interaction.On the other hand,owning to photoluminescence,GQDs also have potential to serve as fluorescence probe for bioimaging,especially for optical diagnostics.In addition,GQDs have the ability to generate reactive oxygen species (ROS)including singlet oxygen upon photoexcitation.Therefore,GQDs are likely to be used for photodynamic therapy.This article aims to review the frontier researches about GQDs in the field of fluorescence probe,photodynamic therapy and anti-tumor drug delivery system.
graphene quantum dots drug delivery system tumor photodynamic therapy
ZHANG You-ying LI Quan WANG Wen-cheng ZHANG Qi-hao HUANG Ya-dong SU Zhi-jian XIANG Qi
College of Pharmacy,Jinan University, Guangzhou 510632, China College of Life Science and Technology, Jinan University, Guangzhou 510632, China Institute of Biomedicine and Guangdong Provincial Key Laboratory of Bioengineering Medicine, Jinan U
国内会议
药学类期刊发展论坛暨庆祝《沈阳药科大学学报》创刊六十周年学术研讨会
沈阳
英文
805-816
2017-12-08（万方平台首次上网日期，不代表论文的发表时间）