Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009-2013
Background: Screening on MDR-TB (multidrug resistant tuberculosis) has been limited to the serious TB subpopulations but excluded the new TB patients.This study aimed to examining MDR-TB burden among the new TB patients.Methods: We did a prospective study in Zhejiang province during 2009-2013 to observe MDR-TB among the five subpopulations of serious TB patients and the new TB patients.The number, prevalence and trend of MDR-TB were compared while the logistic regression model was used to examine risk factors related to MDR-TB.Results: A total of 200 and 791 MDR-TB cases were respectively identified from the 9,830 new TB cases and 2,372 high risk suspects who took MDR-TB screening from 2009 to 2013,respectively.The MDR-TB rates went down in both of the new TB patients and five MDR-TB high risk groups over the study time, but the percentage of MDR-TB patients identified from the new TB patients in all diagnosed MDR-TB cases kept stable from 28.32% in 2011 to 27.03% in 2012 to 26.03% in 2013.Conclusions: The study indicated that MDR-TB burden among new TB patients was high, thus,screening for MDR-TB among the new TB patients should be recommended in China as well as in the similar situation worldwide.
tuberculosis drug resistance MDR-TB screening
Ying Peng Song-Hua Chen Le Zhang Bin Chen Ming-Wu Zhang Tie-Niu He Fei Wang Cheng-Liang Chai Lin Zhou Yu Zhang Xiao-Meng Wang Zhongwei Jia
Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang 310051,China National Institute of Drug Dependence, Peking University, Beijing 100191, China ;Department of Epide National Institute of Drug Dependence, Peking University, Beijing 100191, China
国内会议
杭州
英文
582-595
2017-10-01（万方平台首次上网日期，不代表论文的发表时间）