Radiosensitization by telomerase inhibitor BIBR1532 in human non-small-cell lung cancer
Objective: Radiotherapy continues to be relevant in the treatment of non-small cell lung cancer (NSCLC).Telomerase is repressed in the majority of somatic cells,but reactivated in over 85% of all human cancers,including NSCLC,and could be a promising target to improve radiotherapeutic effects.Here,we investigated the radiosensitizing effect of the highly selective telomerase inhibitor BIBR1532 and the corresponding mechanism in NSCLC in vitro.
Xiaofeng Ding Dong Qian Jingjing Cheng Zhiyong Yuan
Department of radiotherapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China
国内会议
2016年国际肿瘤放射治疗新进展天津论坛暨中国北方肿瘤放射治疗协作组第二届学术会议
天津
英文
241-242
2016-06-03(万方平台首次上网日期,不代表论文的发表时间)