Differentiating crude drugs derived from animal bile using TLC fingerprint profile coupled with chemometric methods

摘要：

　　In this study,the methanol solutions of the seven most common bile-based crude dugs(ZD,ND,YD,XD,NH,TPNH,RGNH)were separated via TLC respectively.The information of TLC pictures was converted into digital pattern.Some chemometric methods,such as KNN,PLS-DA,SVM-DA and SIMCA,were performed in this study based on above processing,and these TLC models .were validated by cross validation and prediction set validation.These results of validation indicated that the seven bile-based crude drugs could be distinguished successfully by this method.

作者: Yan Shi Tianjiao Zheng Feng Wei Shuangcheng Ma

作者单位: National Institutes for Food and Drug Control

会议类型: 国内会议

会议名称: 中国科协第334 次青年科学家论坛—中药质量与安全关键检测技术

会议地点: 北京

会议语种:英文

页码: 45-46

在线出版日期: 2017-11-15（万方平台首次上网日期，不代表论文的发表时间）