Non-steroidal Anti-inflammatory Drugs and Hypertension

摘要：

　　Non-steroidal anti-inflammatory drugs (NSAIDs) are frequently used to alleviate pain of the patients who suffer from inflammatory conditions like rheumatoid arthritis, osteoarthritis, and other painful conditions like gout.This class of drugs works by blocking cyclooxgenases which in turn block the prostaglandin production in the body.Most often, NSAIDs and antihypertensive drugs are used at the same time, and their use increases with increasing age.Moreover, hypertension and arthritis are common in the elderly patients requiring pharmacological managements.An ample amount of studies put forth evidence that NSAIDs reduce the efficiency of antihypertensive drugs plus aggravate pre-existing hypertension or make the individuals prone to develop high blood pressure through renal dysfunction.This review will help doctors to consider the effects and risk factors of concomitant prescription of NSAIDs and hypertensive drugs.

关键词： Non-steroidal anti-inflammatory drugs Hypertension High blood pressure Prostaglandins Antihypertensive drugs Renal injury

作者: Liuying Zheng Kuan Wang Guoxing Zuo Dong Wang Xinping Du

作者单位: The Fifth Central Hospital of Tianjin

会议类型: 国内会议

会议名称: 天津高血压论坛2016暨天津市医师协会高血压专业委员会第一届年会

会议地点: 天津

会议语种:英文

页码: 93-98

在线出版日期: 2016-11-01（万方平台首次上网日期，不代表论文的发表时间）