Antiviral Sesquiterpenes from leaves of Nicotiana tabacum

摘要：

　　Three unreported sesquiterpenes possessing two new skeletons,tabasesquiterpenes A-C(1-3),together with three known sesquiterpenes(3-6)were isolated from the leaves of Nicotiana tabacum.Their structures were determined mainly by spectroscopic methods,including extensive 1D-and 2D NMR techniques.Compounds 1-6 were evaluated for their anti-tobacco mosaic virus(anti-TMV)activities.The results showed that compound 2 exhibited high anti-TMV activity with inhibition rate of 35.2%,which were higher than that of positive control(ningnanmycin).The other compounds also showed potential anti-TMV activity with inhibition rates in the range of 20.5~28.6%,respectively.

关键词： Nicotiana tabacum Sesquiterpenes Tabasesquiterpenes A-C Anti-tobacco mosaic virus activity

作者: Shan-Zhai Shang Wei Zhao Jian-Guo Tang Xing-Meng Xu Han-Dong Sun Jian-Xin Pu Zhi-Hua Liu Ming-Ming Miao Yong-Kuan Chen Guang-Yu Yang

作者单位: Key Laboratory of Tobacco Chemistry of Yunnan Province,China tobacco yunnan industrial Co.,Ltd,Kunmi Key Laboratory of Tobacco Chemistry of Yunnan Province,China tobacco yunnan industrial Co.,Ltd,Kunmi State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany

会议类型: 国内会议

会议名称: 中国烟草学会2017年学术年会

会议地点: 北京

会议语种:英文

页码: 1-15

在线出版日期: 2017-11-01（万方平台首次上网日期，不代表论文的发表时间）