Antioxidant activities in vitro and vivo the ultrasoniccirculating extract powder of Ganoderma sichuanense and its active ingredients
The aim of this study was to compare the antioxidant activities and active ingredients in ultrasonic-circulating extract powder (UCEP) with hot-water extract powder (HWEP) of log-cultivated Ganoderma sichuanense.The DPPH, ABTS, O2-, T-AOA, FRAP assay results showed the UCEP exhibited stronger antioxidant activity in vitro than the HWEP.Meanwhile, the detection of GSH, SOD, MDA in rat liver, ALT, AST, LDH in rat blood, and western blot for antioxidant proteins of TGF-β1, HO-1 and GSH-Px showed that the UCEP had either similar or a little stronger antioxidant activity in vivo when compared with the HWEP.Further analysis of the active ingredients revealed the UCEP and HWEP had the similar average yields and content of total triterpenoids (TTs), but the former had significant higher (P<0.05)average yield and content of total polysaccharides (GLPs) than the latter.).These suggested the potential use of UCEP as an antioxidant and liver protectant.
Ganoderma sichuanense ultrasonic-circulating extraction antioxidant activity hepatoprotective activities,polysaccharide
Chen Ti-Qiang Kan Yong-Jun Yang Chi Wu Jian-Guo Wu Jin-Zhong Wong Ka-Hing
Institute of Edible and Medicinal Fungi, Fujian Academy of Agricultural Sciences, Fuzhou 350014, Chi Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University
国内会议
福建省科协第十六届学术年会分会暨2016年福建省食用菌学会学术年会
福州
英文
144-154
2016-08-20（万方平台首次上网日期，不代表论文的发表时间）