MACC1 in gastric cancer: beyond metastasis

摘要：

　　Metastasis-associated in colon cancer-1 (MACC1) is an oncogene.In gastric cancer (GC),MACC1 is involved in tumor progression.MACC1 overexpression adversely affects clinical outcomes of GC patients.MACC1 promotes the epithelial-to-mesenchymal transition (EMT) and vasculogenic mimicry.MACC1 also facilitates GC lymphangiogenesis by upregulating VEGF-C/D.MACC1 also supports GC growth by enhancing the Warburg effect.In conclusion, MACC1 might be an important mediator of tumor microenvironment.

关键词： Metastasis-associated in colon cancer-1 Gastric cancer Tumor microenvironment

作者: 吴珍珍

作者单位: 南方医科大学南方医院 510515

会议类型: 国内会议

会议名称: 广东省医学会肿瘤内科学分会成立大会暨广东省医学会第一次肿瘤内科学学术会议

会议地点: 广州

会议语种:英文

页码: 134-141

在线出版日期: 2016-08-05（万方平台首次上网日期，不代表论文的发表时间）