Dynamin-3:a novel candidate tumor suppressor

摘要：

　　According to the current survey, Dynamin3(DNM3) is a member of the dynamin family(inciude:DNM1, DNM2, DNM3) of genes that are essential for microtubules, endocytosis, vesicular transport, and shown to be connected with hepatocellular carcinoma, breast cancer, sarcoma, Se”zary syndrome and so on.But to date, the role of dysregulated dynamin-3 expression in malignant diseases hasn”t been researched yet.In this report, we will review the structure and basic function of dynamin-3, then discuss the possible mechanism of dynamin-3 impact on malignant disease.Given the current knowledge of information, We finally propose that dynamin-3 could be a new candidate tumor suppressor gene.

关键词： Dynamin-3(DNM3) dynamin candidate tumor suppressor gene

作者: 张辉洁

作者单位: 广东医科大学附属医院 524001

会议类型: 国内会议

会议名称: 广东省医学会肿瘤内科学分会成立大会暨广东省医学会第一次肿瘤内科学学术会议

会议地点: 广州

会议语种:英文

页码: 160-165

在线出版日期: 2016-08-05（万方平台首次上网日期，不代表论文的发表时间）