Sex moderates the effects of the SORL1 gene rs2070045 polymorphism on cognitive impairment and disruption of the cingulum integrity in healthy elderly

摘要：

Objective The SORL1 rs2070045 polymorphism was reported to be associated with SorLA expression in the brain and the risk of late-onset Alzheimer”s disease (AD).However, the influenceof this poyrnorphism on cognitive functioning is likely to be moderated by sex.This study aimed to examlne the sex moderation on the effectsof rs2070045on neuropsycho ogical performance and the clngulum integrity in Chinese Han population.

作者: He Li Ying Liang Zhanjun Zhang

作者单位: Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing State key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Res State key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Res

会议类型: 国内会议

会议名称: 第三届脑成像与脑电研究与应用研讨会

会议地点: 大连

会议语种:英文

页码: 31-31

在线出版日期: 2016-07-01（万方平台首次上网日期，不代表论文的发表时间）