电子转运裂解质谱特征及其在蛋白质鉴定中的应用
“As we move forward, I predict newer search engines built around ETD fragmentation patterns, rather than adapted from a CAD point of view, will further improve ETD performance.” ETcaD: H atom loss or gain c-type ions can lose a H atom to become c·-type, while z”-type fragments gain the H atom to generate z-type ions.“However, the database search algorithms we used OMSSA) had difficulty with the 1-Da ambiguity of many newly generated fragment ions. I predict that with further development this search algorithm issue will likely be resolved, and we can expect the ETcaD method to offer excellent performance across a very broad precursor m/z range.”
蛋白质 鉴定技术 电子转运裂解质谱特征
孙瑞祥
中科院计算所
国内会议
北京
中文
1-44
2010-11-10（万方平台首次上网日期，不代表论文的发表时间）