骨髓源抑制细胞的发育以及在乳腺癌生长中的作用及功能调节
The CC chemokine ligand5(CCL5)is detected in many clinical specimens of breast and cervical cancers,and its greater plasma levels in patients are associated with a more progressive disease than those in remission. Here, we show that theCCLS一CCRS axis in the bone marrow (BM), independent of its chemotactic activities,plays an essential role in the development of myeloid-derived suppressor cells(MDSCs) and tumor-associated macrophages (TAMS).
乳腺癌 病理机制 骨髓源抑制细胞 细胞发育 生长调节
马小京
上海交通大学生命科学技术学院
国内会议
上海
中文
30-30
2016-04-07（万方平台首次上网日期，不代表论文的发表时间）