Overcoming Tamoxifen Resistance of Human Breast Cancer by RNA Nanotechnology

摘要：

　　Over 70%of human breast cancer expresses estrogen receptor(ER)and selective estrogen receptor modulators(SERMs),such as tamoxifen,have been widely used in their treatments.Unfortunately,up to half of the patients are or soon become resistant to the therapy.Hence,further development of novel strategies to selectively block the activities of this pathway is urgently needed.

关键词： RNA nanotechnology Tamoxifen resistance Estrogen receptor MED1 Breast Cancer

作者: Yijuan Zhang Marissa Leonard Peixuan Guo Xiaoting Zhang

作者单位: Department of Cancer Biology,University of Cincinnati College of Medicine,Cincinnati 45267,USA Nanobiotechnology Center,University of Kentucky College of Pharmacy,Kentucky 40536,USA

会议类型: 国内会议

会议名称: The 6th International Conference on Nanoscience and Technology, China 2015 (第六届中国国际纳米科学技术会议)

会议地点: 北京

会议语种:英文

页码: 109-109

在线出版日期: 2015-09-03（万方平台首次上网日期，不代表论文的发表时间）