Serum metabolome biomarkers associate low-level environmental perfluorinated compound exposure with oxidative/nitrosative stress in humans

摘要：

Humans are ubiquitously exposed to perfluorinated compounds(PFCs),and these pollutants have been detected in blood and tissues worldwide.Previous in-vivo and in-vitro studies have linked metabolism interruption with PFC exposure.However,biological differences among species and the use of high experimental doses often make animal test results difficult to interpret with regard to human relevance.The best strategy for identification of the disturbances in environmental health will be to set up studies directly targeted on human population.So far,the metabolic response to low-level environmental PFC exposure is not reported for epidemiology.

关键词： metabolome perfluorinated compound serum oxidative/nitrosative

作者: Jie Zhang Xiaofei Wang Heqing Shen

作者单位: Key Lab of Urban Environment and Health,Institute of Urban Environment,Chinese Academy of Sciences,China

会议类型: 国内会议

会议名称: 第21届全国色谱学术报告会

会议地点: 成都

会议语种:英文

页码: 276-277

在线出版日期: 2017-05-19（万方平台首次上网日期，不代表论文的发表时间）