Sensitive and precise measurement of phosphatidylethanol in human blood as a biomarker for alcohol intake by LC-MS/MS

摘要：

Phosphatidylethanol(PEth) is a class of special phospholipids only formed in the presence of ethanol and therefore,serves as a promising biomarker for alcohol intake ”1,2”.In this study,a simple,rapid and precise method based on LC-MS/MS was developed and validated for the measurements of PEth(16:0/18:1,16:0/18:2,16:0/16:0,and 18:1/18:1) in human blood.

关键词： Phosphatidylethanol Ethanol Alcohol intake Ultrasound-assisted dispersive liquid-liquid microextraction Tandem mass spectrometry

作者: Siming Wang Jun Dong Yueming Tang Ruiyue Yang Hongxia Li

作者单位: The MOH Key Laboratory of Geriatrics,Beijing Hospital,National Center of Gerontology,Beijing 100730

会议类型: 国内会议

会议名称: 第21届全国色谱学术报告会

会议地点: 成都

会议语种:英文

页码: 330-330

在线出版日期: 2017-05-19（万方平台首次上网日期，不代表论文的发表时间）