BioSynther:a customized biosynthetic potential explorer
Motivation: One of the most promising applications of biosynthetic methods is to produce chemical products of high value from the ready-made chemicals.To explore the biosynthetic potentials of a chemical as a synthesis precursor,biosynthetic databases and related chemoinformatics tools are urgently needed.In the present work,a web-based tool,BioSynther,is developed to explore the biosynthetic potentials of precursor chemicals using BKM-react,Rhea,and more than 50000 inhouse RxnFinder reactions manually curated.BioSynther allows researchers to explore biosynthetic potentials,through so far known biochemical reactions,step by step interactively,which could be used as a useful tool in metabolic engineering and synthetic biology.
Weizhong Tu Haoran zhang Juan Liu Weizhong Tu
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery(Wuhan University),Ministry of Educat State Key Laboratory of Software Engineering(Wuhan University)and Wuhan Uniwrsity School of Computer Key Laboratory of Combinatorial Biosynthesis and Drug Discovery(Wuhan University),Ministry of Educat
国内会议
大连
英文
82-83
2016-09-24（万方平台首次上网日期，不代表论文的发表时间）