Guidelines for Validation of Next-Generation Sequencing-Based Oncology Panels:A Joint Consensus Recommendation of the Association for Molecular Pathology and College of American Pathologists

摘要：

Determining required depth of sequencing Binomial distribution of true positives(TPs) calculated-given an allele burden of 5％and 250 read depth Binomial distribution of false positives(FP) calculated given an error rate of 1％

作者: Lawrence J.Jennings Maria E.Arcila Christopher Corless Suzanne Kamel-Reid Ira M.Lubin John Pfeifer Robyn L.Temole-Smolkin Karl V.Voelkerding Marina N.Nikiforova

会议类型: 国内会议

会议名称: 第六届肿瘤分子病理检测标准化应用及质量控制研讨会

会议地点: 上海

会议语种:英文

页码: 1-27

在线出版日期: 2017-07-28（万方平台首次上网日期，不代表论文的发表时间）