Purpose: There have been few reports on the development of metabolic disorders,especially when they are considered as a cluster.The purpose of this study was to deserve risk profiles for metabolic syndrome (MetS) in elderly dwellers in Beijing, and to find their transition patterns over time.Data were derived from Beijing Longitudinal Study of Aging, a community-based-cohort study hosted by Xuanwu hospital.There were 3,257 elderly people aged 55 years or over recruited in 1992.MetS was assessed for the years 1992, 2000 and 2009.Finally, 363 subjects with complete information for components of MetSin the three years were included in the study.The criteria of MetS recommended by the Joint Interim Statement criteria were adopted.Latent transition analysis (LTA) was used to calculate the transition probabilities between adjacent visits.A risk typology consisting of fourtime-invariant groups was detected based on the components of MetS for all subjects.Low MetS risk group, BP risk group, BP-HDL risk group, and BP-FPG-TG risk group were found.The probability of staying at the same status was higher at the two intervals across 18 years.Fourlatent groups were extracted based on three assessments for the components of MetS, together with their transition patterns.Findings suggestedvarious trajectories for MetS components.Different combinations of interventionstrategy might be needed for MetS risk groups.
Metabolic syndrome Elderly Latent transition analysis Longitudinal study
Lixin Tao Wei Wang Huiping Zhu Da Huo Tao Zhou Lei Pan Qi Gao Yanxia Luo Lijuan Wu Xia Li Zhe Tang Xiuhua Guo
School of Public Health, Capital Medical University, Beijing 100069, China;Beijing Municipal Key Lab Department of Integrated Early Childhood Development, Capital Institute of Pediatrics,Beijing 100020 Institute for Infectious Disease and Endemic Disease Control, Beijing Center for Disease Prevention School of Public Health, Capital Medical University, Beijing 100069, China;Beijing Municipal Key Lab Xuanwu Hospital, Capital Medical University, Beijing 100053, China;Beijing Geriatric Clinical and Re School of Public Health, Capital Medical University, 10 Xitoutiao,Youanmenwai, Fengtai, Beijing 1000