Objective: To examine the associations of combined lifestyle factors and physical conditions with cerebrovascular diseases (CBVD) mortality, after accounting for competing risk events, including death from cardiovascular diseases, cancers and other diseases.Methods: Data on 2010 subjects aged over 55 years were finally analyzed using competing risk models.All the subjects were interviewed by the Beijing Longitudinal Study of Aging (BLSA), in China, between 1 January1992 and 30August 2009.Results: Elderly females were at a lower risk of death from CBVD than elderly males (HR=0.639, 95%CI=0.457-0.895).Increasing age (HR=1.543, 95% CI=1.013-2.349), poor self-rated health (HR=1.652, 95%CI=1.198-2.277), hypertension (HR=2.201, 95% CI=1.524-3.178) and overweight (HR=1.473, 95%CI=1.013-2.142) or obesity (HR=1.711, 95% CI=1.1754-2.490)was associated with higher CBVD mortality risk.Normal cognition function (HR=0.650, 95% CI=0.434-0.973) and living in urban (HR=0.456, 95% CI=0.286-0.727) was associated with lower CBVD mortality risk.Gray”s test also confirmed the cumulative incidence (CIF) of CBVD was lower in the ”married” group than those without spouse,and the mortality was lowest in the ”nutrition sufficient” group among the ”frequent consumption of meat group” and the ”medial typegroup” (P value<0.001).Conclusions: CBVD mortality was associated with gender, age, blood pressure, residence, BMI, cognitive function, nutrition and the result of self-rated health assessment in the elderly in Beijing, China.
Cerebrovascular diseases Cohort study Competing risk model Risk factors
Zhe Tang Tao Zhou Yanxia Luo Changchun Xie Da Huo Lixin Tao Lei Pan Fei Sun Huiping Zhu Xinghua Yang Wei Wang Aoshuang Yan Xia Li Xiuhua Guo
Beijing Geriatric Healthcare Center, Xuan Wu Hospital, Capital Medical University, Beijing, China School of Public Health, Capital Medical University, Beijing, China;Beijing Municipal Key Laboratory Division of Epidemiology and Biostatistics, Department of Environmental Health, University of Cincin Institute for Infectious Disease and Endemic Disease Control, Beijing Center for Disease Prevention School of Medical Science, Edith Cowan University, Australia School of Public Health, Capital Medical University, Beijing, China;Beijing Municipal Science and Te School of Public Health, Capital Medical University, Beijing, China;Epidemiology and Public Health,