Effect of Abnormal Savda Munziq on the Oxidative Stress Response of Parkinson”s Disease Rat Models
OBJECTIVE: To observe the effects of Abnormal Savda Munziq (ASMq) on the behavior and oxidative stress response of Parkinson”s disease (PD) rat models.METHODS: PD rats were produced by stereotactic injection of 6-OHDA into the substantia nigra compacta (SNc) and the midbrain ventral tegmental area (VTA) of the right side of the brain.We set up regular blank control group and the PD models were randomly divided into the model blank control group, the madopar group (madopar 125 mg/kg), and the low, middle and high dose of ASMq group (1 g/kg, 3 g/kg, 6 g/kg), and each group had 10 rats.The behavior of each group rats was observed before and after 40 days of treatment.After the treatment, each group got randomly 2 rats for the immunohistochemical detection for the quantity change of tyrosine hydroxylase (TH) expression.
J.P.Liu E.Mahsum X.L.Yang
Senior Cadre Ward, the First Affiliated Tumor Hospital of Xinjiang Medical University,Urumqi, China Institute of Urumqi Medicine of Xinjiang Medical University, Urumqi, China
国内会议
苏州
英文
362-363
2015-09-11（万方平台首次上网日期，不代表论文的发表时间）