Non-synchronic Alteration of Clathrin and PICALM Involved in the Endocytosis in Aβ1-42 Treated Neurons In Vivo

摘要：

OBJECTIVE: Recent studies have shown that endocytosis involves in the mechanisms of Alzheimer”s disease (AD).Clathrin and phosphatidylinositol binding clathrin assembly protein (PICALM), as key proteins of clathrin-mediated endocytosis (CME),probably participate in the CME dysfunction in AD development.Hence, the aim of the present study was to investigate the relationship between CME and AD via the alteration of Clathrin and PICALM.

作者: R.Shi Y.Lü

作者单位: Department of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

会议类型: 国内会议

会议名称: 2015中国老年医学和老年健康产业大会

会议地点: 苏州

会议语种:英文

页码: 365-365

在线出版日期: 2015-09-11（万方平台首次上网日期，不代表论文的发表时间）