Salidroside Stimulates Mitochondrial Biogenesis in a Cellular Senescence Model of Human Fibroblasts
OBJECTIVE: To investigate the effect of salidroside (SAL) on delaying cellular senescence according to our previous work.METHODS: SA-Gal (senescence associated Galactosidase) staining was used to evaluate the senescent population of WI-38 ceils.Intracellular reactive oxygen species (ROS) and mitochondrial mass (MM) were measured by flow cytometry using H2DCFDA (2”,7”-dichlorodihydrofluorecein diacetate) and NAO (nonylacridine orange), respectively.
G.X.Mao X.L.L.Lv Y.Z.Wang G.F.Wang J.Yan
Provincial Key Lab of Geriatrics & Geriatrics Institute of Zhejiang Province, Zhejiang Hospital, Hangzhou, China
国内会议
苏州
英文
366-366
2015-09-11(万方平台首次上网日期,不代表论文的发表时间)