Sirtinol Suppresses Human Cytomegalovirus (hCMV) Infection and hCMV-induced Cellular Senescence and Production of Reactive Oxygen Species in Human Fibroblasts

摘要：

BACKGROUND: Human cytomegalovirus (hCMV) causes birth defects in newborns and severe infections in immunocompromised patients.hCMV also contributes to immunosenescence.AntihCMV treatments are limited with significant drawbacks.We aimed to investigate effects of sirtinol, a sirtuin inhibitor, on CMV-induced cellular senescence.

作者: G.X.Mao H.F.Li G.F.Wang S.X.Leng

作者单位: Zhejiang Provincial Key Laboratory of Geriatrics & Geriatrics Institute of Zhejiang Province, Zhejia Division of Geriatric Medicine and Gerontology, Department of Medicine, Johns Hopkins University Sch

会议类型: 国内会议

会议名称: 2015中国老年医学和老年健康产业大会

会议地点: 苏州

会议语种:英文

页码: 1-2

在线出版日期: 2015-09-11（万方平台首次上网日期，不代表论文的发表时间）