Candesartan Effects on Insulin Sensitivity of the Skeletal Muscle in Spontaneously Hypertensive Rats

摘要：

BACKGROUND: Candesartan is one of the angiotensin Ⅱ receptor blockers (ARBs) known to reduce blood pressure through direct inhibition of the binding between the angiotensin Ⅱ and their receptors on vascular smooth muscle cells.In recent years, many clinical studies have found that ARBs can reduce the incidence of diabetes.It is hypothesized that candesartan could improve the body”s insulin sensitivity by blocking the angiotensin Ⅱ disruptive effect on skeletal muscle cells.This study was designed to investigate the effects and mechanism of candesartan on insulin resistance of the skeletal muscle in spontaneously hypertensive rats (SHR).

作者: F.Li L.Ye H.Huang Q.Zeng

作者单位: International Medical Center, Chinese PLA General Hospital,Beijing 100853, China

会议类型: 国内会议

会议名称: 2015中国老年医学和老年健康产业大会

会议地点: 苏州

会议语种:英文

页码: 28-29

在线出版日期: 2015-09-11（万方平台首次上网日期，不代表论文的发表时间）