Expression of TREM2 and CARD9 in a Mouse Model of Alzheimer”s Disease

摘要：

OBJECTIVE: Recent studies show that inflammation plays an important role in mechanisms of Alzheimer”s disease (AD).Triggering receptor expressed on myeloid cells 2 (TREM2), which is a receptor on the surface of microglial membrane, and is closely tied to AD.Caspase recruitment domain containing protein 9 (CARD9) is an adaptor protein, and one study suggests that further TREM signal requires CARD9 in the dendritic cells.This study aimed to evaluate the relationship between them and AD.

作者: M.Gu Y.Lü

作者单位: Department of Geriatrics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China

会议类型: 国内会议

会议名称: 2015中国老年医学和老年健康产业大会

会议地点: 苏州

会议语种:英文

页码: 104-105

在线出版日期: 2015-09-11（万方平台首次上网日期，不代表论文的发表时间）