Depleted Aldehyde Dehydrogenase1A1 Reverses Cisplatin Resistance of Non-small Cell Lung Cancer Cells A549/DDP

摘要：

OBJECTIVE: Cisplatin is the first-line chemotherapy for the treatment of non-small cell lung cancer (NSCLC).However, its resistance has been a major obstacle in the management of NSCLC.Aldehyde dehydrogenaselA1 (ALDH1A1) over-expression has been observed in a variety of cancers, including lung cancer.The purpose of this study was to investigate the effect of ALDH1A1 expression on cisplatin resistance and to explore potential mechanism.

作者: Y.Y.Wei S.S.Wu W.Xu Y.Liang J.Q.Wu

作者单位: Department of Geriatrics, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China

会议类型: 国内会议

会议名称: 2015中国老年医学和老年健康产业大会

会议地点: 苏州

会议语种:英文

页码: 108-109

在线出版日期: 2015-09-11（万方平台首次上网日期，不代表论文的发表时间）