Effect of Different Intermittent Hypoxia on Hippocampal Neuron Autophagy

摘要：

PURPOSE: Cognitive dysfunction is one of the common complications in elderly patients with obstructive sleep apnea hypopnea syndrome (OSAHS).Intermittent hypoxia (IH), a major pathological component of OSAHS, can induce hippocampal neuronal injury.It is likely that IH-induced hippocampal neuronal injury may be a major mechanism to the cognitive dysfunction.Autophagy is an important pathophysiological mechanism for maintaining intracellular homeostasis.In our study, we aimed to investigate the intermittent hypoxia-induced autophagy in hippocampal neurons.

作者: Y.Y.Fang J.Tan Q.Zhang P.Lei L.Wang

作者单位: Tianjin Institute of Geriatrics, Tianjin Medical University General Hospital, Anshan Road, Tianjin 300052, China

会议类型: 国内会议

会议名称: 2015中国老年医学和老年健康产业大会

会议地点: 苏州

会议语种:英文

页码: 112-113

在线出版日期: 2015-09-11（万方平台首次上网日期，不代表论文的发表时间）