A Comparative Study in the Very Old Patients Treated with Different Antiplatelet Agents
OBJECTIVE: The aim of this study was to investigate and compare antiplatelet effects and side-effects of combination therapy with different antiplatelet agents in the very old patients (≥ 75 years).METHODS: A total of 263 patients aged 75 years old or over with cardiovascular diseases were included in the study.Patients were randomly divided into seven groups: aspirin 100mg, aspirin 100mg plus marzulene-s 0.67g, plavix 75mg, aspirin 100mg plus plavix 75mg, talcom 50mg,plavix 75mg plus PPIs, and the placebo group.The treatment lasted for 16 weeks.Before and at the end of the study, gastroscopy was performed to detect gastrointestinal bleeding.Blood specimens were collected in all eligible patients to test blood routine values, prothrombin time (PT),prothrombin activity (PA), activated partial thromboplastin time (APTT), fibrinogen (FIB), and platelet aggregation rate (PAG).
K.L.Li Q.J.Si
Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing,China Healthcare Department 2, Hainan Branch of Chinese PLA General Hospital, Sanya,China
国内会议
苏州
英文
142-142
2015-09-11（万方平台首次上网日期，不代表论文的发表时间）