Gene Signature in Plasma and Tumor Predicts Irinotecan Chemosensitivity in Gastric Cancer

摘要：

Background: Personalized chemotherapy based on molecular biomarkers can maximum efficiency and reduce adverse effects.Methods: We examined gene expression of APTX, BRCA1, ERCC1, ISG15, and Topo1 in plasma and paired gastric cancer tissues from 175 patients and evaluated the association between gene levels and sensitivity to irinotecan.

作者: 沈洁 魏嘉 丁义涛 钱晓萍 禹立霞 邹征云 管文贤 刘宝瑞

作者单位: The Comprehensive Cancer Centre of Drum Tower Hospital, Medical School of Nanjing University, Clinic Department of Surgery, Drum Tower Hospital Affiliated to the Medical School of Nanjing University

会议类型: 国内会议

会议名称: 第九届中国肿瘤内科大会、第四届中国肿瘤医师大会暨中国抗癌协会肿瘤临床化疗专业委员会2015年学术年会

会议地点: 北京

会议语种:英文

页码: 722-722

在线出版日期: 2015-07-01（万方平台首次上网日期，不代表论文的发表时间）