Photo-induced self-assemblyof proteins and related protein-drug nano-assemblies for drug delivery

摘要：

Disulfide bonds buried in proteins can be ruptured by UV illumination which triggers the unfolding of these proteins that further self-assemble into different kinds of aggregates.Under UV illumination with low intensity, chicken egg white lysozyme (CEWL) can aggregate into fibrils through newly formed intermolecular disulfide bonds following a runaway domain-swapping mechanism”1”.

作者: Wei Wang

作者单位: School of Physics, Nanjing University, Nanjing 210093, China

会议类型: 国内会议

会议名称: 国家自然科学基金委员会“可控自组装体系及其功能化”重大研究计划年度交流暨研讨会

会议地点: 南京

会议语种:英文

页码: 173-173

在线出版日期: 2014-02-20（万方平台首次上网日期，不代表论文的发表时间）