Metabolic engineering of Escherichia coli to enhance acetol production from glycerol

摘要：

Acetol,a C3 keto alcohol,is an important intermediate used to produce polyols and acrolein.To enhance acetol production from glycerol by Escherichia coli,a mutant (HJ02) was constructed by replacing the native glpK gene with the allele from E.coli Lin43 and overexpression of yqhD,which encodes aldehyde oxidoreductase YqhD that converts methylglyoxal to acetol.

作者: Ruilian Yao Qing Liu Hongbo Hu Thomas K.Wood Xuehong Zhang

作者单位: StateKey Laboratory of Microbial Metabolism,School of Life Sciences and Biotechnology,Shanghai Jiao Department of Chemical Engineering,Pennsylvania State University,University Park,PA 16802-4400,USA

会议类型: 国内会议

会议名称: 中国生物工程学会第六次全国会员代表大会暨第九届学术年会

会议地点: 上海

会议语种:英文

页码: 1-2

在线出版日期: 2015-11-06（万方平台首次上网日期，不代表论文的发表时间）