Exposure of Metal Nanoparticles to Simulated Biological Fluids: Strong Degradation or High Persistence?
(0) The lack of data on nanoparticle physicochemical behaviour in biological liquids does not allow giving deep interpretation of nanoparticles toxicity and elaborating modern comprehensive approaches for nanomaterials biotesting.The aim of this study was to examine the degradation degree of composition and morphology of engineered electroexplosive zinc and aluminum nanoparticles exposed to simulated biological fluids(artificial sweat,simulated saliva,simulated gastric fluid,artificial lysosomal fluid,glucose solution).Using scanning electron microscopy and X-ray analysis it has been revealed that differently composed nanoparticles may demonstrate both high physicochemical degradation and persistence in simulated biological fluids,whereas the degree of persistence/degradation depends on test-solution properties.
aluminum and zinc nanoparticles degradation dispersity composition morphology simulated biological fluid toxicity
Elizaveta Karepina Elena Yunda Anna Godymchuk Denis Kuznetsov
Tomsk Polytechnic University,Lenina ave.,30,Tomsk,634050,Russia Tomsk Polytechnic University,Lenina ave.,30,Tomsk,634050,Russia;National University of Science and T National University of Science and Technology “MISIS”,Leninsky ave.,4,Moscow,119049,Russia
国内会议
哈尔滨
英文
994-1001
2015-09-18（万方平台首次上网日期，不代表论文的发表时间）