Inhibition of ZEB 1 Reverses the Phenotype of Epithelial-Mesenchymal Transition and Chemoresistance in Docetaxel-Resistant Human Lung Adenocarcinoma Cell Line SPC-A1/DTX

摘要：

Docetaxel has been used as one of the first-line chemotherapies in solid tumors including advanced non-small cell lung cancer (NSCLC).However, limited responses to chemotherapy are observed in clinic and the molecular mechanisms have not been fully understood.Emerging evidence suggests that epithelial-mesenchymal transition (EMT) plays an important role in the processes of tumor metastasis as well as resistance towards anticancer agents.

作者: 任琎 王锐 陈龙邦

作者单位: 210002 南京军区南京总医院肿瘤内科

会议类型: 国内会议

会议名称: 第十六届全国临床肿瘤学大会暨2013年CSCO学术年会

会议地点: 厦门

会议语种:英文

页码: 334-335

在线出版日期: 2013-09-25（万方平台首次上网日期，不代表论文的发表时间）