Knockdown of CREB3/Luman by shRNA in mouse granulosa cells results in decreased estradiol and progesterone synthesis and promotes cell proliferation

摘要：

Luman (also known as LZIP and CREB3) is a transcription factor and a member of the cAMP responsive element-binding (CREB) family proteins.Although Luman has been detected in apoptotic granulosa cells and disorganized atretic bodies, the physiological function of Luman in follicular development has not been reported.Our objective was to determine the role of Luman in folliculogenesis by knocking down Luman expression in mouse GCs (granulosa cells) using shRNA.

作者: Fan Zhao Nan Wang Yaping Jin

作者单位: Key Laboratory of Animal Biotechnology,Ministry of Agriculture,Northwest A&F University,Yangling Shaanxi 712100,China;College of Veterinary Medicine,Northwest A& F University,Yangling Shaanxi 712100,China

会议类型: 国内会议

会议名称: 中国畜牧兽医学会兽医产科学分会第十三次学术研讨会

会议地点: 浙江宁波

会议语种:英文

页码: 75-75

在线出版日期: 2016-10-22（万方平台首次上网日期，不代表论文的发表时间）