Montanide ISA 71 R VG:A robust and flexible adjuvant formulation for potent and stable poultry vaccines
Water-in-mineral oil emulsion adjuvants induce a strong long-term immune response and arewidely used in inactivated poultry vaccines.As chickens receive multiple vaccines,multivalentvaccines are more and more used in the field to decrease the number of injections.Robustadjuvants that allow flexible ratio of oil and antigenic media in the vaccine are required for theformulation of multivalent vaccines.Moreover,destabilization of multivalent vaccine emulsion formulations can be observed during storage when high concentration of enzymes is present inantigenic media or in non-adapted storage conditions.Resistant formulations are therefore neededto ensure stability of vaccines,especially for multivalent bacterial vaccines.We have thus developed a new adjuvant resistant to destabilizing antigenic media and conditions,and that canbe used at flexible ratio in poultry vaccines.
Francois Bertrand Juliette Ben Arous Jér(o)me Gaucheron Laurent Dupuis
SEPPIC China,580 West Nan Jing Road,Shanghai 200041,China SEPPIC,22 Terrasse Bellini,Paris La Défense,92806 Puteaux Cedex,France
国内会议
重庆
英文
7-7
2015-04-16（万方平台首次上网日期，不代表论文的发表时间）