Curative Effects of SuhuangZhike Capsule on Post-infectious Cough: a Meta-Analysis of Randomized Controlled Trials
Objective: In this paper, we intended to systematically evaluate the efficacy of SuhuangZhike Capsule (SZC) on post-infectious cough (PIC) in adults (age >18).Methods: Medline (Pub Med), Chinese National Knowledge Infrastructure (CNKI), Cqvip Database (VIP), Wanfang Database were researched for the randomized controlled trials (RCTs) of SZC for PIC.The search was limited to human studies, using the search keywords or free-text terms ”cough,” ”post-infectious cough,” ”post-infectious cough,” ”post-cold cough,” ”post-viral cough,” ”post-cold cough,” ”SuhuangZhike capsule, Chinese Medicine,” and ”randomized clinical trials”.Two reviewers individually extracted data from the included RCTs and then the extracted data were analyzed using Review Manager 5.3 software.Results: Seven RCTs involving 573 patients entered the inclusion criteria.Findings suggested that, compared with western conventional medicine (WCM) and other Chinese medicine, SZC could effectively improve the efficacy rate (OR 2.68.95%CI, 1.48-4.84.P=0.001;OR 4.86.95%CI, 1.50-15.73.P=0.008, separately.).Moreover, SZC could also improve the efficacy rate of Chinese medicine symptom (MD-0.74.95%CI, -1.46~-0.02.P=0.04).However, in terms of cough relief time, more evidence is needed to prove that SZC have an earlier antitussive effect (MD-1.31.95%CI, -3.06~0.45.P=0.14).Conclusion: The current evidence shows that SZC is effective in the treatment of PIC in adults, and can significantly improve the effective rate of Chinese medicine symptoms.
SuhuangZhike Capsule Postinfectious Cough Post-cold Cough Randomized Controlled Trials Meta-Analysis
Qian Wang Pinpin Ding Jing Yao Xianmei Zhou Jia Zhu
Department of Respiratory Medicine, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210029, China
国内会议
贵州兴义
英文
392-409
2016-08-25（万方平台首次上网日期，不代表论文的发表时间）