Mdivi-1 prevents apoptosis induced by ischemia/reperfusion injury in primary hippocampal cells via inhibition of ROS-activated mitochondrial pathway

摘要：

1.Introduction Ischemic-reperfusion (I/R) injury causes brain neurons structural and functional damage, which is one of the most important reasons of disability and mortality.Neuronal apoptosis is known a vital mechanism that lead to cell death after oxygen-glucose deprivation followed by reperfusion, so the relationship between cell-apoptosis and UR injury has stimulated great interest in the development of brain anti-apoptosis therapies.The brain consumes 1/5 of the body”s oxygen, so neurons are sensitive to hypoxia.

作者: 王金英 王鹏 李淑虹 王士雷 李瑜 梁楠 王敏

会议类型: 国内会议

会议名称: 山东省第十七次麻醉学学术会议

会议地点: 烟台

会议语种:英文

页码: 280-287

在线出版日期: 2014-07-01（万方平台首次上网日期，不代表论文的发表时间）