Inhibiting glucose transporter-1 and the PI3K/Akt pathway with apigenin, siRNA, LY294002 or wortmannin affects the radiosensitivity of laryngeal squamous cell carcinoma in vitro and in vivo

摘要：

　　Background We first hypothesized that targeting glucose transporter-1 (GLUT-1) and the phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt) pathway might improve the radiosensitivity of laryngeal cancer.

关键词： Laryngeal carcinoma,glucose transporter-1,PI3K/Akt pathway,radiosensitivity small interfering RNA,Ly294002,wortmannin

作者: Shui-Hong Zhou Yang-Yang Bao Li-Bo Dai Zhong-Jie Lu Ya-Ping Huang Ting-Ting Wu

作者单位: Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang Universit Department of Radiotherapy, The First Affiliated Hospital, College of Medicine, Zhejiang University, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospit

会议类型: 国内会议

会议名称: 第十五次中国中西医结合耳鼻咽喉科专业委员会年会

会议地点: 浙江宁波

会议语种:英文

页码: 274-275

在线出版日期: 2016-07-29（万方平台首次上网日期，不代表论文的发表时间）