Different outcomes after intracytoplasmic sperm injection without oocyte activation in two patients with globozoospermia
Different outcomes after intracytoplasmic sperm injection (ICSI) without oocyte activation in two patients with round-headed spermatozoa (globozoospermia) are reported.After controlled ovarian hyperstimulation and oocyte pick-up, retrieved oocytes were underwent ICSI without oocyte activation and a 33.33% (4/12) fertilization rate was obtained in the first case;whereas an abnormal fertilization (polyspermy) was achieved in the second case.The transfer of two grade Ⅱ embryos in the first couple resulted in clinical pregnancy with a healthy livebirth.It was concluded that the main problem of cases with globozoospermia is a low fertilization rate even a failure fertilization, and even though ICSI and artifical oocyte activation have been employed to increase this rates, however this may not be useful or necessary in all patients.
globozoospermia intracytoplasmic sperm injection (ICSI) acrosome assisted oocyte activation (AOA) human assisted reproductive technology (ART)
Zhi-Qin Zhang Zhi-Hui Huang Cai-Lin Xin Qing-Fang Wu
Department of Human Assisted Reproductive, Jiangxi Maternity and Child Healthcare Hospital, No.381 Ba-yi Rd, Nanchang City 330006, Jiangxi, PR China
国内会议
南昌
英文
195-199
2014-10-01（万方平台首次上网日期，不代表论文的发表时间）