The correlation between microRNA and invasion, metastasis, diagnosis, treatment,prognosis of lung cancer
Lung cancer is one of the most common malignant tumors in the world scope, and has become the top cause of death awaug caucers in our country.Despite improvements in early diagnosis and newly developed therapies,the 5-year survival rate is extremely low.MiRNA is a kind of endogenous,highly conserved non-coding small RNA molecules, and about 30% of the genes in the human body can be adjusted by miRNA, playing an important role in physiological processes, such as growth and development, cell reproduction, metabolism, apoptosis, et al.Alterations of the expression of miRNA have increasingly been associated with pathophysiologic changes of cancer cells, making miRNAs currently to be one of the most analyzed molecules in cancer research.In recent years, the research that serving miRNAs as molecular markers for early diagnosis, invasion and metastasis, prognostic and efficacy prediction developed rapidly.This review summarized the correlation in miRNAs and invasion and metastasis, diagnosis.treatment, prognosis of lung cancer.
Lung cancer miRNAs invasion and metastasis diagnosis treatment prognosis
TONG Jia-bing LI Ze-geng
Anhui University of TCM,Hefei Anhui 230038
国内会议
重庆
英文
118-127
2016-08-01（万方平台首次上网日期，不代表论文的发表时间）