Signal Transductions and nonalcoholic fatty liver:a mini-review

摘要：

　　Nonalcoholic fatty liver disease(NAFLD) is a common liver disease,and the incidence increases year by year.The pathogenesis of NAFLD is correlated with insulin resistant(IR),and oxidative stress which induces varied inflammatory cytokines(TNF-α,IL-1,IL-6 etc).Different signal transductions such as MAPK,NF-κB,AMPK,JAK2/STAT3,PPAR,PI3K/Akt,TLR were activated by the pathogenic factors to regulate correlative reactions.Thus,in-depth study of the signal transductions will probably provide new suitable solutions for the prevention and therapy of NAFLD.

关键词： nonalcoholic fatty liver disease pathogenesis signal transduction

作者: Lu Zeng Waijiao Tang Jingjing Yin Benjie Zhou

作者单位: Department of Pharmacy,Zhu-Jiang Hospital,Southern Medical University,Guangzhou510280,China

会议类型: 国内会议

会议名称: 2015广东省药师周大会

会议地点: 广州

会议语种:英文

页码: 1-9

在线出版日期: 2014-12-20（万方平台首次上网日期，不代表论文的发表时间）