The Stem cell factor/Kitsignaling pathway regulates mitochondrial function and energy expenditure

摘要：

Cell growth is tightly coupled with mitochondrial biogenesis in order to maintain energy and organelle homeostasis.Receptor tyrosine kinase Kit and its ligand,stem cell factor (SCF),play a critical role in the growth and survival of multiple cell lineages.Here we report thatthe expression of SCF and Kit in adipose tissues is responsive to food availability and environmental temperature,and is altered in obese mice and human patients.

作者: Gao Xiang

作者单位: Nanjing University, Nanjing, Jiangsu 210093 ,China

会议类型: 国内会议

会议名称: 第三届“模式生物与人类健康”发育遗传学全国学术研讨会

会议地点: 厦门

会议语种:英文

页码: 9-9

在线出版日期: 2014-07-17（万方平台首次上网日期，不代表论文的发表时间）