Mechanisms of gut stem cell regulation and homeostasis in Drosophila

摘要：

Adult tissue homeostasis is maintained by resident stem cells and their progeny.However,the underlying mechanismscontrolling tissue homeostasis are not fully understood.Morphogens such as BMP,Hh and Wnt,are essential for developmental patterning.Our studies demonstrated that trachea-derived Decapentaplegic(Dpp),the main BMP ligand in Drosophila,is essential for adult midgut homeostasis.Our study provided important insights into the roles of BMP signaling in inter-organ communication.

作者: Xinhua Lin

作者单位: State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, P.R.China

会议类型: 国内会议

会议名称: 第三届“模式生物与人类健康”发育遗传学全国学术研讨会

会议地点: 厦门

会议语种:英文

页码: 27-27

在线出版日期: 2014-07-17（万方平台首次上网日期，不代表论文的发表时间）