Neuroprotective effect of acute ethanol administration in cerebral ischemia through inhibiting adenosine phosphate-activated protein kinase (AMPK) Pathway

摘要：

　　Various epidemiologic studies in recent years have indicated that light/moderate alcohol consumers have lower risks of nerve degenerative disease,suggesting that ethanol have neuroprotective effect.Ethanol is known to be involved in many signaling pathway,such as AMPK,protein kinase B/AKT and protein kinase C.Recently,some researches found that acute ethanol have neuroprotective effect,the mechanisms underlying it (acute ethanol-induced) are not completely understood.Integrating existing related research,it will be interesting to explore whether inhibit AMPK levels after acute ethanol administration is one of the mechanisms for neuroprotective effect.

作者: Xialin Zuo Ping Wu Xiaoxia Liu Li Liu Qian Xu Aimin Ji

作者单位: Center for Drug Research and Development,zhujiang Hospital,Southern Medical University,Guangzhou 510282,P.R.China

会议类型: 国内会议

会议名称: 2013年广东省药师周大会

会议地点: 广州

会议语种:英文

页码: 462-469

在线出版日期: 2013-01-12（万方平台首次上网日期，不代表论文的发表时间）