Brachytherapy of Intermediate High Risk Prostate Cancer

摘要：

For intermediate-and high-risk prostate cancer, brachytherapy is often combined with external beam radiation therapy(EBRT) to supplement the radiation dose to other tissues atrisk, including the seminal vesicles.Combined therapymay increase the risk ofnormal tissue injury comparedwith that associated with the useof either modality alone.Some reports have reportedincreased morbidity after combined brachytherapy and EBRT.In our previous study, we found that Grade 2 rectal bleedingwas significantly correlated with the use of supplemental EBR T and that analysis of the rectal dose-volume histogram(DV-H) for brachytherapy and EBRT was a useful method for predictingthe risk of development of Grade 2 rectal bleeding.Furthermore, we evaluate the predictive value of equivalent uniform doses (EUD) for late rectal toxicity after I-125brachytherapy for prostate cancer.EUD may be amore useful predictive indicator of late rectal toxicity than known post-implant dosimetric parameters.

作者: Yutaka Shiraishi

作者单位: Keio University, Japan

会议类型: 国内会议

会议名称: 北京大学医学部放射肿瘤学系成立大会暨北京大学第二届国际放射肿瘤学术论坛

会议地点: 北京

会议语种:英文

页码: 401-401

在线出版日期: 2012-05-23（万方平台首次上网日期，不代表论文的发表时间）