Biotransformation: a promising technology for anti-cancer drugs development

摘要：

　　With the high morbidity and mortality caused by cancer,finding more and better anti-cancer drugs is very urgent.In current research,biotransformation plays a vital role in the research and development of cancer drugs and has obtained some achievements.In this review,we have thoroughly summarized the four applications as follows:to exploit novel anti-cancer drugs,to improve existing anti-cancer drugs,to broaden limited anti-cancer drugs resources and to investigate correlative mechanism.Three different groups of important anti-cancer compounds would also be shown so as to clarify the current practical application of biotransformation in the development of anti-cancer drugs.

关键词： Biotransformation Anti-cancer drugs Development Practical application

作者: Fei Gao Jinming Zhang Zhanguo Wang Wei Peng Huiling Hu Chaomei Fu

作者单位: State Key Laboratory Breeding Base of Systematic Research,Development and Utilization of Chinese Med State Key Laboratory of Quality Research in Chinese Medicine,Institute of Chinese Medical Sciences,U College of Life Sciences,Sichuan University,Chengdu,Sichuan,PR China

会议类型: 国内会议

会议名称: 2013年全国博士生学术论坛——中药资源系统研究与开发利用

会议地点: 成都

会议语种:英文

页码: 602-619

在线出版日期: 2013-11-01（万方平台首次上网日期，不代表论文的发表时间）