TRPC3 and TRPC6 channel blockers inhibit background calcium influx and modulate calcium transients in mouse muscle fibers

摘要：

We have recently shown that the cation channels TRPC3 and C6 are expressed in mouse skeletal muscle.Here we studied whether the unspecific TRPC channel blocker 2-APB and/or the specific blocker Pyr3(TRPC3) and ML-9 (TRPC6) affect muscular Calcium homeostasis.To investigate divalent cation influxwe used single interosseus muscle fibers and applied the Manganese quench technique.

作者: Yaxin Zhang Bernd Pritschow Heinrich Brinkmeier

作者单位: Institute of pathophysiology,University of Greifswald

会议类型: 国内会议

会议名称: 2013北京国际神经病学会议

会议地点: 北京

会议语种:英文

页码: 68-68

在线出版日期: 2013-04-19（万方平台首次上网日期，不代表论文的发表时间）