Hematopoietic stem cells from Ts65Dn mouse bone marrow are deficient in the repair ofDNA double-strand breaks

摘要：

Down syndrome(DS) is the most common chromosomal abnormality in humans caused by the presence of all or part of a third copy of chromosome 21.In addition to musculoskeletal and neurodevelopmental abnormalities,pediatric patients with DS also display various hematologic disorders and are atincreased risk of acute lymphoblastic leukemia and acute megakaryocyticleukemia.

作者: Yingying Wang Jianhui Chang Lijian Shao Janie Rae Byrum Wei Feng Yi Luo Daohong Zhou Marie Chow Aimin Meng

作者单位: Institute of Radiation Medicine,Chinese Academy of Medical Sciences & Peking Union Medical Collage,T Division of Radiation Health,Department of Pharmaceutical Sciences,University of Arkansas for Medica Department of Microbiology and Immunology,University of Arkansas for Medical Sciences,Little Rock,Ar Institute of Radiation Medicine,Chinese Academy of Medical Sciences & Peking Union Medical Collage,T

会议类型: 国内会议

会议名称: 第二届全球华人辐射研究大会

会议地点: 苏州

会议语种:英文

页码: 96-97

在线出版日期: 2014-05-11（万方平台首次上网日期，不代表论文的发表时间）