Minocycline Protects Whole-Brain Irradiation-Induced Neurons Apoptosis and Cognitive Impairment in Rats

摘要：

As an important treatment modality for brain tumor patients,cranial radiotherapy causes a debilitating cognition decline thus decreasing the quality of patients” life.Therefore,intense investigation is being carried out to look for effective ways to overcome this side effect.The objective of this study was to investigate whether minocycline,an antibiotic that has demonstrated neuroprotective properties in a variety of experimental models of neurological diseases,has protective effects on irradiation-induced damage in hippocampus and cognitive impairment.

作者: Liyuan Zhang Kun Li Ye Tian Peigeng Huang Hongying Yang

作者单位: Department of Radiotherapy and Oncology,Second Affiliated ospital,Soochow University,1055 Sanxiang R Department of Radiation Oncology,Massachusetts General Hospital,Harvard Medical School,100 Blossom S School of Radiation Medicine and Protection,Medical College of Soochow University/School for Radiolo

会议类型: 国内会议

会议名称: 第二届全球华人辐射研究大会

会议地点: 苏州

会议语种:英文

页码: 99-100

在线出版日期: 2014-05-11（万方平台首次上网日期，不代表论文的发表时间）