Infarct morphology assessment in patients with carotid artery/middle cerebral artery occlusion using Fast fluid-attenuated inversion recovery (FLAIR) vascular hyperintensity (FVH)
Background : Cerebral angiography has been the gold standard for the assessment of intracranial collateral circulation currently; however it has not been widely applied due to the disadvantages such as invasiveness and high costs.We aimed to evaluate the value of fast fluid-attenuated inversion recovery (FLAIR) vascular hyperintensity (FVH) in assessing infarct morphology in patients with symptomatic internal carotid artery (ICA) or middle cerebral artery (MCA)occlusions.Methods: Magnetic resonance (MR) diffusion-weighted imaging (DWI) and FLAIR sequences, and carotid/cerebral magnetic resonance angiography (MRA) were obtained from 102consecutive prospective study patients with symptomatic ICA or MCA occlusions.The location and score of FVH were evaluated according to Olindo”s method, and the patients were diagnosed as Low FVHs and High FVHs based on FVH score, and Distal FVH and Proximal FVHbased on FVH location.The differences between infarct morphologies were analyzed in these patients.Results: FVH were detectable in 62 (60.8%) patients were diagnosed as High FVHs and40 (39.2%) patients were Low FVHs based onOlindo”s scale ≥ 4 or < 4.There were no statistically significant differences in age, gender, hypertension, diabetes, hyperlipidemia, smoking history and vascular occlusive site between High and Low FVHs patients (P> 0.05) except for infarct morphology (P<0.01).Patients with Distal FVH presented with significant (P< 0.01) perforating artery infarct and border zone infarct, whereas those Proximal FVH had significant (P<0.01) large territorial infarcts.Conclusion: The scores and locations of FVH might be a predictive imaging marker for infarct morphology in symptomatic ICA or MCA occlusion.
FLAIR vascular hyperintensity carotid artery or middle cerebral artery occlusion infarct morphology
Dengyue Zhai Youling Zhu
Department of Neurology, the Third Affiliated Hospital of Anhui Medical University, Huaihe Road 390, Hefei 230061, Anhui Province, China
国内会议
安徽芜湖
英文
332-341
2015-11-01（万方平台首次上网日期，不代表论文的发表时间）